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目的研究托特罗定对经尿道前列腺电切术(TURP)后短期症状的改善作用。方法64例拟行TURP的患者被分为两组,治疗组(n=33)于术后给以口服托特罗定直至拔导尿管后14d,对照组(n=31)不服用托特罗定,分别记录术前和拔管后1、7、14、28d的国际前列腺症状评分(IPSS)、梗阻症状评分和刺激症状评分,两组间进行比较。结果治疗组拔管后7、14d的IPSS和刺激症状评分明显低于对照组(P<0.05),两组间梗阻症状评分没有差异。拔管后28d两组的尿流率、残余尿比较无差异(P>0.05)。结论托特罗定可以改善BPH患者TURP术后的早期症状,并且不影响尿流率和残余尿。
Objective To study the effect of tolterodine on short-term symptoms after transurethral resection of the prostate (TURP). Methods Totally 64 TURP patients were divided into two groups. The treatment group (n = 33) was given oral tolterodine until 14 days after catheterization, while the control group (n = 31) did not take Tudor Luo Ding, were recorded before and after extubation 1,7,14,28 d International Prostate Symptom Score (IPSS), obstruction symptoms and irritation symptoms were compared between the two groups. Results The scores of IPSS and irritation symptom in the treatment group at 7 and 14 days after extubation were significantly lower than those in the control group (P <0.05). There was no difference in the symptom score between the two groups. After extubation 28d urinary flow rate, residual urine no difference (P> 0.05). Conclusion Tolterodine improves early symptoms after TURP in BPH patients without affecting urinary flow rate and residual urine.