0引官汉滩病毒属布尼亚病毒科汉坦病毒属，主要引起人类肾综合征出血热，我国是肾综合征出血热发生和流行的主要疫区．故寻找安全有效、低廉的疫苗是控制本病流行和发生的关键”’，基因免疫是将编码外源蛋白的核酸表达质粒直接转化到机体，以激发机体产生针对外源蛋白的特异性 0 cited Hantaan virus Bunyavirus Hantavirus genus, mainly caused by human renal syndrome hemorrhagic fever, our country is the occurrence and prevalence of hemorrhagic fever with the main epidemic area. Therefore, looking for safe, effective and low-cost vaccine is the key to controlling the epidemic and the occurrence of this disease. “” Gene immunization transforms the nucleic acid expression plasmid encoding the foreign protein directly into the body to stimulate the body to produce the specificity for the foreign protein