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本文报道４２例急性心肌梗塞（ＡＭＩ）患者血清线粒体天门冬氨酸转氨酶（ｍ－ＡＳＴ）活力的动态变化，多数ＡＭＩ患者血清ｍ－ＡＳＴ活力在发病后１２ｈ明显增高，２４ｈ可高达峰值。ｍ－ＡＳＴ诊断ＡＭＩ的敏感度１００％，特异性９３．５％，与ＣＫ—ＭＢ相似（Ｐ＞０．２０），可作为ＡＭＩ诊断的酶学指标。但本文尚未证实ｍ－ＡＳＴ对ＡＭＩ有预后评估价值。
This article reports the dynamic changes of mitochondrial aspartate aminotransferase (m-AST) activity in 42 patients with acute myocardial infarction (AMI). The serum m-AST activity of most patients with AMI was significantly increased at 12h after onset and peaked at 24h. The sensitivity and specificity of m-AST in the diagnosis of AMI were 100% and 93.5%, respectively, which were similar to those of CK-MB (P> 0.20). However, this study has not confirmed the prognostic value of m-AST for AMI.