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目的 探讨高血压病左心室肥厚与心律失常的关系。方法 选择2001-2003年上海交通大学附属第一人民医院心内科246例原发性高血压患者,进行静息同步12导联心电图,动态心电图及超声心动图测定,监测左室重量指数等指标。结果 左心室肥厚组平均左室重量指数水平为(151.6±15.8)g/m~2,和左心室正常者相比差异有显著性(P<0.01)。左心室肥厚组定性心律失常及复杂性定性心律失常的检出率为93.27％和51.92％,明显高于左心室正常组(35.21％,10.56％),差异有显著性(P<0.001)。结论 原发性高血压左心室肥厚相关性心律失常,尤其是复杂性心律失常,与左室肥厚的程度及是否合并左房肥大有明确的规律关系。
Objective To investigate the relationship between left ventricular hypertrophy and arrhythmia in hypertensive patients. Methods 246 patients with essential hypertension in Department of Cardiology, First People ’s Hospital Affiliated to Shanghai Jiao Tong University from 2001 to 2003 were enrolled in this study. Resting synchronous 12 - lead electrocardiogram, ambulatory electrocardiogram and echocardiography were performed to monitor left ventricular mass index. Results The average LV mass index of left ventricular hypertrophy group was (151.6 ± 15.8) g / m ~ 2, which was significantly different from that of normal left ventricle group (P <0.01). The positive rates of qualitative arrhythmia and complicated qualitative arrhythmia in left ventricular hypertrophy group were 93.27% and 51.92%, respectively, which were significantly higher than those in normal left ventricle group (35.21%, 10.56%) (P <0.001). Conclusion Essential hypertension associated with left ventricular hypertrophy arrhythmia, especially complex arrhythmia, and left ventricular hypertrophy and whether the degree of consolidation of left atrial hypertrophy have a clear regular relationship.