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神经干细胞对颅内胶质瘤有很强的趋向作用,而对正常脑组织无此特性。TRAIL能选择性地促使肿瘤细胞凋亡而对正常组织无毒性。本文就神经干细胞、TRAIL及神经干细胞转染TRAIL后与胶质瘤的关系作一综述。
Neural stem cells have a strong tendency to intracranial gliomas, but not to normal brain tissue. TRAIL selectively induces apoptosis of tumor cells without toxicity to normal tissues. This article reviews the relationship between neural stem cells, TRAIL and neural stem cells transfected with TRAIL and glioma.