认识播散性念珠菌病具有的特征性皮肤损害,有可能对这种常常致死的真菌感染进行早期诊断和治疗.由于缺乏特殊的体征和症状,这种致死性真菌感染死前常不能诊断.因为大多数这种感染是由随处可见的念珠菌种所引起,除非从血液中培养出病原菌,否则解释阳性培养结果是困难的.Bodey报告,血液培养阳性的,仅占被尸体解剖证实的播散性念珠菌病患者的25%.广泛器官受累虽然是播散性念珠菌病的特征,但报告皮肤损害者甚少.本文叙述可推断播散性念珠菌病临床诊断的皮肤所见. Recognizing the characteristic skin lesions associated with disseminated candidiasis makes it possible to diagnose and treat this often lethal fungal infection, which can often not be diagnosed due to the absence of specific signs and symptoms. Because most of this infection is caused by the prevalence of Candida species, explaining positive culture results is difficult unless pathogenic bacteria are cultured from the blood, and Bodey reports that blood cultures are positive and account for only the necropsy confirmed by autopsy 25% of patients with disseminated candidiasis. Although extensive organ involvement is characteristic of disseminated candidiasis, few are reported for skin lesions. This article describes the skin findings that can be used to infer the clinical diagnosis of disseminated candidiasis.