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目的探讨双乳突低频电刺激治疗对急性脑梗死后认知障碍的影响。方法以2012年1月至2014年10月廓坊市第四人民医院神经内科收治的98例急性脑梗死患者为研究对象,按入院顺序分组,奇数入对照组,偶数入电刺激组,每组49例。对照组患者给予脱水降颅压、抗血小板聚集、活血化淤、改善脑细胞代谢及预防并发症等常规药物治疗。电刺激组在药物常规治疗的基础上实施双乳突低频电刺激治疗。治疗前和治疗后采用蒙特利尔认知评测量表(Mo CA)、连线测验A型、词语流畅性测验、数字符号测验、数字广度分测验评定认知功能。结果对照组与电刺激组在性别、年龄、受教育年限、梗死灶位置及面积、伴其他疾病等方面比较差异无统计学意义(P>0.05);治疗后2周,电刺激组和对照组在各项认知测验评分较治疗前有改善,差异有统计学意义(P<0.05),两组在Mo CA评分、词语流畅测验、数字符号测验等方面比较,差异有统计学意义(P<0.05),电刺激组分数较对照组提高更明显;治疗后3个月,电刺激组在连线测验A方面均较治疗后2周有进一步改善(P<0.05),对照组在各项认知测验方面与治疗后2周相比均有下降(P<0.05),电刺激组在各项认知测验方面均明显好于对照组(P<0.05);治疗后6个月,电刺激组各项认知测验与治疗后3个月相比差异无统计学意义(P>0.05),对照组在各项认知测验分数均进一步下降,差异有统计学意义(P<0.05)。结论双乳突低频电刺激对急性脑梗死后认知障碍具有明显的治疗作用。
Objective To investigate the effect of low-frequency electrical stimulation of double-mastoid process on cognitive impairment after acute cerebral infarction. Methods From January 2012 to October 2014, 98 patients with acute cerebral infarction admitted to the Fourth People’s Hospital of Contour City were enrolled in the order of hospital admission, odd number control group and even number into electrical stimulation group. Each group 49 cases. Patients in the control group were given dehydration intracranial pressure, anti-platelet aggregation, blood stasis, improve brain cell metabolism and prevent complications and other conventional drug treatment. Electrical stimulation group in the conventional treatment of drugs based on the implementation of low-frequency electrical stimulation of mastoidectomy. Before and after treatment, the Montreal cognitive assessment scale (MoCA), connection test type A, word fluency test, digital sign test and digital breadth test were used to evaluate cognitive function. Results There were no significant differences in sex, age, years of education, location and size of infarction and other diseases between the control group and the electrical stimulation group (P> 0.05). After 2 weeks of treatment, the electrical stimulation group and the control group There was significant difference between the scores of cognitive tests before treatment (P <0.05). There was significant difference between the two groups in terms of MoCA score, smooth fluent word test and digital sign test (P < 0.05), and the number of electrical stimulation group was more obvious than that of the control group. In the three months after treatment, the electrical stimulation group was further improved in the connection test A by two weeks after treatment (P <0.05) Compared with the control group, the electrical stimulation group was significantly better than the control group (P <0.05), and the electrical stimulation group There was no significant difference between the three cognitive tests and the three months after the treatment (P> 0.05). The scores of cognitive tests decreased further in all cognitive tests (P <0.05). Conclusions Double-mastoid low-frequency electrical stimulation has a significant therapeutic effect on cognitive impairment after acute cerebral infarction.