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目的探讨多次重复体外冲击波碎石(ESWL)对病人的不良反应。方法我们对2000年10月至2006年5月多次(5次以上、冲击次数1000/次)ESWL的57例肾、输尿管结石病人进行了6个月至6年的随访。结果血Cr、BUN、γ-谷氨酰转移酶(γ-GT)和尿β2-微球蛋白(β2-MG)的平均值在正常范围;继发高血压2例、发生率3.7%。部分病例震波侧肾脏的肾小球滤过率有所下降。结论多次ESWL对肾脏可能造成一定的损害,应掌握ESWL的适应症。
Objective To investigate the adverse reactions of repeated extracorporeal shock wave lithotripsy (ESWL) to patients. METHODS: 57 patients with renal and ureteral calculi ESWL from October 2000 to May 2006 were followed up for 6 months to 6 years with multiple ESWL episodes (more than 5 episodes per impact). Results The average values of blood Cr, BUN, γ-glutamyl transferase (γ-GT) and urinary β2-microglobulin (β2-MG) were in the normal range; secondary hypertension occurred in 2 cases, the incidence was 3.7%. In some cases, the glomerular filtration rate of the shock side of the kidney decreased. Conclusions ESWL may cause some damage to the kidneys. The indication of ESWL should be mastered.