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纳洛酮是一种吗啡拮抗剂,有报告2例蛛网膜下腔出血应用该药后偏瘫暂时好转。作者报告13例发病24小时内的急性卒中病人应用纳洛酮静脉注射后其临床症状逆转的试验。13例的症状从孤立的失语到昏迷不等,其病因包括脑出血、脑血栓和栓塞。用生理盐水作单盲对照试验,10分钟后注射纳洛酮0.8～1.2mg。经观察,注射生理盐水后均无变化,而用药后有3例显示症状立即好转,其余9例未见即刻治疗效应。仅在1例脑出
Naloxone is a morphine antagonist, there are reports of 2 cases of subarachnoid hemorrhage after temporary improvement of the drug. The authors report 13 patients with acute stroke within 24 hours after intravenous injection of naloxone clinical symptoms reversed test. The symptoms of 13 patients range from isolated aphasia to unconsciousness, and their causes include cerebral hemorrhage, cerebral thrombosis and embolism. A single-blind control test with normal saline, naloxone 0.8 ~ 1.2mg after 10 minutes. After observation, there was no change after injection of saline, and 3 cases showed immediate improvement after treatment, and the other 9 cases showed no immediate therapeutic effect. Only one case of brain out