[美国]/Guan N…//N Engl J Med,2009,360(11):1067-1074.背景:最近在中国流行的三聚氰胺污染的婴幼儿奶粉被认为与泌尿道结石的发生有关,虽然其临床表现和易患因素尚未完全阐明。方法:我们对接受三聚氰胺暴露史、泌尿系结石症状及可能的易患因素筛查的36月龄或小于36月龄的婴幼儿的父母进行了问卷调查。此外,我们进行了尿液分析、肾功和肝功检查、尿液生化指标和钙肌酐比检测以及超声波检查。婴儿配方奶粉分为高三聚氰胺含量(>500μg/kg)、中三聚氰胺含量(>150μg/kg)和不含三聚氰胺(Oμg/kg);没有奶粉的三聚氰胺含量介于150～ Background: Recent melamine-contaminated infant formula in China is considered to be associated with urolithiasis, although its Clinical manifestations and risk factors have not been fully elucidated. METHODS: We conducted a survey of parents of infants aged 36 months or younger who underwent melamine exposure, urolithiasis screening, and possible predisposing factors. In addition, we conducted urinalysis, renal and liver function tests, urine biochemical markers and calcium creatinine ratio tests and sonography. Infant formula is divided into high melamine content (> 500μg / kg), melamine content (> 150μg / kg) and melamine (Oμg / kg); melamine content without milk powder is between 150 ~