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目的:观察芪风固表颗粒对烟熏致慢支ICR小鼠脏器系数及肺肠组织中s Ig A的影响。方法提前两周给ICR小鼠芪风固表颗粒然后烟熏八周,取材后测肺、脾、胸腺指数,测肺泡灌洗液和结肠组织测s Ig A含量。结果与模型组比较芪风固表颗粒高、中、低剂量组肺指数降低,脾、胸腺系数明显升高,肺肠组织中s Ig A明显升高。结论芪风固表颗粒能明显改善慢支小鼠的脏器系数增加分泌型s Ig A含量。
OBJECTIVE: To observe the effect of QiFuGu Tablets on the organ coefficient of smokers ICR mice and s Ig A in lung tissue. Methods ICR mice were given sfFGF for two weeks in advance and then smoked for eight weeks. Lung, spleen and thymus index were measured and the content of sAG A was measured in BALF and colon tissues. Results Compared with the model group, the lung index, the spleen index and the thymus index in the high, middle and low doses of QiFuGu Tablets were significantly increased, while the s Ig A in the lung tissues were significantly increased. Conclusion Qifenggu Tablets can significantly improve the organ index of chronic bronchitis mice to increase the secretion of s Ig A content.