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目的:检测青木香(AristolochiadebillisSieb.etZucc.)的块根水提取液的消炎和镇痛效果及毒性。方法:用蛋清诱导法、热板法和扭体法。结果:青木香的块根水提取液无毒性,1000mg/kg,i.g.的青木香块根水提取液比生理盐水的消炎和镇痛效果明显,比200mg/kg,i.g.乙酰水杨酸的消炎效果好,2000mg/kg,i.g.的青木香块根水提取液比乙酰水杨酸的消炎效果更加显著。结论:青木香具有较好消炎和镇痛活性,无毒性。
Objective: To detect the anti-inflammatory and analgesic effects and toxicity of root extract of Aristolochiadebillis Sieb.et Zucc. Methods: egg white induction method, hot plate method and writhing method. Results: The root water extract of Aristolochia debilis was not toxic, and the water extract of A. odoratum at 1000 mg/kg, ig was more effective than normal saline in anti-inflammatory and analgesic effects, and had better anti-inflammatory effect than 200 mg/kg, ig acetylsalicylic acid. 2000mg/kg, ig Aqueous root water extract than acetylsalicylic acid anti-inflammatory effect is more significant. Conclusion: Aristolochia fragrans has good anti-inflammatory and analgesic activity without toxicity.