论文部分内容阅读
消化性溃疡是一种常见病,大约每10个西德居民中有一人至少曾患过一次。常用治疗药物非常多,但经有对照的临床研究证明有效的溃疡药却很少。怀疑论者面对这一问题时,便提出溃疡是自愈的疾患的说法。但因消化性溃疡在两年之内约有40～50％复发,故还应致力于阐明溃疡病的病因和病理生理学。溃疡病研究的实际结果,可以简短地概括为:如无盐酸存在,肯定无溃疡形成;已证明有效的药物仅有抗酸剂(能减轻痛苦)和生胃酮(Carbenoxolon能促进胃溃疡愈合)。在致溃疡性胰岛细胞瘤(旧称Zollinger-Ellison综合征)中溃疡病发生的盐酸学说得到了证实:在人类用促胃液素长期刺激胃分泌时也可引起
Peptic ulcer disease is a common disease that affects at least one out of every 10 West German residents. Commonly used therapeutic drugs are very large, but controlled clinical studies have shown that there are few available ulcer drugs. When skeptics face this issue, they say that ulcers are a healed illness. However, peptic ulcer recurrence in about 40 ~ 50% within two years, it should also be committed to elucidating the etiology and pathophysiology of ulcer disease. The actual results of the study on ulcer disease can be briefly summarized as: no ulcer is surely formed in the absence of hydrochloric acid; antacids (which can relieve pain) and carbenoxolone (Carbenoxolon can promote healing of gastric ulcer) have been shown to be effective only . Hydrochloric acid theory of ulcer disease has been demonstrated in ulcerative pancreatic islet cell tumors (formerly Zollinger-Ellison syndrome): this may also be caused when human gastric ulcer is stimulated by gastric juice for a long time