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目的比较体外受精-胚胎移植(IVF-ET)和单精子卵胞浆内注射(ICSI)的妊娠结局。方法对安徽省妇幼保健院2012年1月至2013年11月436个IVF-ET及117个ICSI治疗患者的临床资料进行回顾性分析,分别比较两组的临床妊娠率、流产率、异位妊娠率。结果 IVF-ET组与ICSI组患者的临床妊娠率(35.53%、34.19%)、流产率(14.7%、12.5%)、异位妊娠率(7.05%、5%)的差异均无统计学意义(P>0.05)。结论 ICSI组与IVF-ET组的临床妊娠结局、流产情况及异位妊娠结局相似,提示ICSI显微操作并不增加妊娠风险。
Objective To compare the pregnancy outcomes of IVF-ET and ICSI. Methods Clinical data of 436 patients with IVF-ET and 117 ICSI treated in Anhui MCH from January 2012 to November 2013 were retrospectively analyzed. Clinical pregnancy rate, miscarriage rate, ectopic pregnancy rate. Results The clinical pregnancy rate (35.53%, 34.19%), miscarriage rate (14.7%, 12.5%) and ectopic pregnancy rate (7.05%, 5%) in IVF-ET group and ICSI group were not significantly different P> 0.05). Conclusions Clinical pregnancy outcome, miscarriage and ectopic pregnancy outcome in ICSI group and IVF-ET group are similar, suggesting that ICSI micromanipulation does not increase the risk of pregnancy.