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SARS冠状病毒(SARS-CoV)严重威胁人类的健康,对其深入研究具有重要的现实意义。许多研究表明,SARS-CoV的S糖蛋白(spike glycoprotein)为其主要抗原,在病毒与宿主细胞表面受体结合并介导病毒经膜融合进入细胞中起关键作用。SARS-CoV病毒S蛋白的N末端含有由疏水性氨基酸组成的短
SARS Coronavirus (SARS-CoV) is a serious threat to human health and has important practical significance for its further study. Numerous studies have shown that SARS-CoV’s spike glycoprotein is its major antigen and plays a key role in the binding of the virus to the host cell surface receptors and to mediate the fusion of the virus into the cell. The N-terminus of the SARS-CoV virus S protein contains a short hydrophobic amino acid