11例难治性慢性多关节炎患者接受20Gy剂量的全淋巴结照射。11例中的4例在治疗过程巾临床症状已经不断好转,其余的在最后两个月,临床症状继续改善。1例患者关节积脓持续到治疗后的26个月。4例死亡,两例死于全身淀粉样变性病中肾功能不全和手术后心原性休克。第3例患者由于多发性关节积脓,死于败血症及中毒性左心衰竭。另外一例,脓肿发展到卡波济氏综合征术后,患者死于急性左心衰竭。治疗使淋巴细胞减少,在T-抑制细胞数不变时,T-辅助 Eleven patients with refractory chronic polyarthritis underwent 20 Gy doses of total lymph node irradiation. Four of the 11 patients had clinical signs of worsening during the course of the treatment and the rest had continued to improve in the last two months. One patient had empyema lasting 26 months after treatment. Four were fatal, and two died of renal insufficiency and postoperative cardiogenic shock in systemic amyloidosis. The third patient died of septicemia and toxic left heart failure due to multiple empyema. In another case, patients developed acute left heart failure after developing abscesses to Kaposi’s syndrome. T lymphocytes are reduced by treatment and T-helper when the number of T-suppressor cells is constant