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对来自不同海拔高度的高原地区25例小儿重症肺炎所致的急性呼吸衰竭患儿,进行了临床与实验室检查等项目的观察,认为:①高原地区小儿急性呼吸衰竭的血气诊断标准,应与平原地区有所区别,以PaO_2≤6kPa、PaCO_2≥5.33kPa为合适;②呼衰组患儿的血清AST、CK、HBD、GGT等活性酶的测定明显高于健康对照组,反映了呼衰所致的多系统器官受损害的程度;③高原地区小儿呼衰由于缺氧与器官微循环流态紊乱的因素,多系统器官功能衰竭的发生率高,且症状更严重。
The clinical and laboratory examinations of 25 children with acute respiratory failure caused by severe pneumonia in children from different altitudes were observed. The results showed that: ① The diagnostic criteria of blood gas in children with acute respiratory failure in the plateau should be PaO2≤6kPa and PaCO_2≥5.33kPa were suitable for the plain areas; ② The activity of AST, CK, HBD, GGT and other active enzymes in the respiratory failure group was significantly higher than that in the healthy control group, Caused by multiple system organ damage degree; ③ plateau area respiratory failure due to hypoxia and organ microcirculation flow disorders, the incidence of multiple system organ failure, and the symptoms are more serious.