论文部分内容阅读
目的初步探讨辅助生殖技术(IVF/ICSI)中异位妊娠(EP)发生的危险因素。方法回顾性分析我院2001年1月-2008年12月接受IVF/ICSI助孕的7798个周期,其中临床妊娠3005个周期(周期妊娠率为38.5%),异位妊娠147个周期(异位妊娠发生率为4.89%),对可能影响正常妊娠导致异位妊娠的因素进行多因素logistic多元回归分析。结果在IVF/ICSI过程中,输卵管积水、促排卵药物使用史、hCG日内膜的厚度、移植胚胎质量与EP的发病明显相关。结论输卵管原因不孕是辅助生殖技术中EP发生的主要相关因素。移植周期合并输卵管积水、既往有输卵管手术史(本治疗周期无输卵管积水)、既往有促排卵药物使用史可增加EP的发生风险;增加hCG日内膜厚度及移植胚胎的质量均可降低IVF/ICSI后EP的发生风险。
Objective To investigate the risk factors of ectopic pregnancy (EP) in assisted reproductive technology (IVF / ICSI). Methods A retrospective analysis of our hospital from January 2001 -2008 in December IVF / ICSI assisted pregnancy 7798 cycles, of which 3005 cycles of clinical pregnancy (cycle pregnancy rate was 38.5%), 147 cycles of ectopic pregnancy (ectopic Pregnancy rate was 4.89%), multivariate logistic multiple regression analysis of the factors that may affect normal pregnancy leading to ectopic pregnancy. Results IVF / ICSI process, tubal hydrops, ovulation induction drug history, hCG day intimal thickness, the quality of embryos transferred and the incidence of EP was significantly correlated. Conclusions Infertility due to fallopian tube is the main factor related to EP in assisted reproductive technology. Transplanted cycle combined with hydrosalpinx, history of tubal surgery (the treatment cycle without hydronephrosis), previous history of ovulation induction drugs can increase the risk of EP; increased hCG day intimal thickness and the quality of embryos can be reduced Risk of EP after IVF / ICSI.