干燥综合征 (Sjogren’s syndrom e,SS)是首先由瑞典眼科学家 Henrik Sjogren于 1 933年提出的一组口眼干燥与风湿性疾病相关联的症候群 [1 ] ,人们后来发现 SS病人的眼泪及唾液的缺乏是其自身免疫反应引起外分泌腺体损伤所致的结果。早在 6 0年代初期人们就发现了 Ig G 有四个 Sjogren’s syndrom e (SS) is a group of dry mouth and rheumatic diseases syndrome first proposed by the Swedish ophthalmologist Henrik Sjogren in 1933 [1]. Later, it was found that SS patients’ tears and saliva The lack of its own immune response caused by exocrine gland damage caused by the results. As early as the early 1960s, one discovered four IgGs