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许多恶性肿瘤起病隐匿,进展快,易复发。初次诊断时已处于中、晚期,多数已失去了手术切除的指征。化学治疗是治疗恶性肿瘤的传统方法之一,而一般的化学药物治疗可造成严重的不良反应,甚至是致命的,且传统的化疗药物也易使癌细胞产生耐药性。因此需要进一步探寻一种安全有效的新型化疗药物以减少传统化疗药物所带来的不良反应。大量的临床前及临床研究发现姜黄素具有抗消化系统肿瘤的作用~[1-2]。本文就姜黄素抗消化系统肿瘤的作用及其分子机制综述如下。
Many malignant tumors occult onset, rapid progress, easy to relapse. Initial diagnosis has been in the late, most have lost the indication for surgical resection. Chemotherapy is one of the traditional methods of treating malignant tumors. However, common chemotherapy drugs can cause serious adverse reactions, even fatal, and traditional chemotherapeutic drugs can easily make cancer cells resistant. Therefore, we need to further explore a safe and effective new chemotherapeutic drugs to reduce the adverse effects of traditional chemotherapy drugs. A large number of preclinical and clinical studies have found that curcumin has anti-digestive system tumors ~ [1-2]. This article on curcumin anti-digestive system tumors and its molecular mechanisms are summarized below.