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目的观察探讨重复经颅磁刺激治疗脑卒中后迟发性癫痫患者的不良效果。方法选取2015年5月至2016年6月来我院就诊治疗的86例脑卒中后迟发性癫痫患者作为实验对象,采用随机法将患者分成观察组与对照组,各43例,对照组使用常规治疗及康复训练,观察组使用常规治疗、康复训练及重复经颅磁刺激治疗。比较分析两组治疗后汉密尔顿焦虑量表(HAMA)、抑郁量表(HAMD)及神经功能缺损程度(NFDS)得分。结果观察组患者的HAMA及HAMD评分分别是(13.7±3.1)分、(15.4±3.2)分,对照组对应分别是(17.7±3.9)分、(22.4±3.6)分,观察组显著低于对照组,P<0.05;观察组NFDS得分为(12.2±3.2)分,对照组(16.2±4.0)分,对照组明显高于观察组,差异较大具有统计学意义。结论重复经颅磁刺激治疗脑卒中后迟发性癫痫效果较好,能有效改善患者焦虑抑郁状态界神经功能缺损程度,值得使用与推广。
Objective To investigate the adverse effects of repeated transcranial magnetic stimulation in patients with delayed epilepsy after stroke. Methods Totally 86 patients with post-stroke delayed epilepsy treated in our hospital from May 2015 to June 2016 were selected as the experimental subjects. The patients were divided into observation group and control group by randomized method, 43 cases in each group. The control group Routine treatment and rehabilitation training, the observation group using conventional therapy, rehabilitation training and repeated transcranial magnetic stimulation therapy. The scores of Hamilton Anxiety Scale (HAMA), Depression Rating Scale (HAMD) and Neurological Deficiency (NFDS) score were compared between the two groups after treatment. Results The scores of HAMA and HAMD in the observation group were (13.7 ± 3.1) and (15.4 ± 3.2) points respectively, while those in the control group were (17.7 ± 3.9) and (22.4 ± 3.6) points respectively. The observation group was significantly lower than the control group (P <0.05). The score of NFDS in the observation group was (12.2 ± 3.2) points and in the control group (16.2 ± 4.0) points, the control group was significantly higher than the observation group, the difference was statistically significant. Conclusions Repeated transcranial magnetic stimulation is effective in treating post-stroke delayed-onset epilepsy and can effectively improve the degree of neurological deficits in patients with anxiety and depression, which is worth using and promoting.