Effect of homocysteine on plaque formation and oxidative stress in patients with acute coronary synd

来源 :中华医学杂志(英文版) | 被引量 : 0次 | 上传用户:zhangf123456
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Background Cardiovascular diseases, especially coronary artery disease (CAD), are major causes of death in industrialized countries. Elevated concentrations of plasma homocysteine (Hcy) have been associated with an increased risk of CAD. Increased plasma levels of chemokine, characterized by their ability to induce migration and activation of leukocytes, may contribute to the pathogenesis of CAD. This study was designed to investigate the changes of plasma Hcy, monocyte chemoattractant protein-1 (MCP-1) and oxidative stress markers in acute coronary syndrome patients.Methods A total of 149 subjects were divided into four groups: 50 patients with unstable angina, 30 patients with acute myocardial infarction, 20 coronary restenosis patients after percutaneous coronary intervention and 49 healthy control subjects. Plasma levels of Hcy, MCP-1, malondialdehyde and superoxide dismutase were measured.Results Plasma levels of Hcy and MCP-1 showed significant increases in unstable angina, acute myocardial infarction and restenosis patients compared with control subjects (P
其他文献
使用农药化肥防治病虫害是蔬菜种植的必要措施之一。随着农村经济的快速发展和农业生产规模的不断扩大,农药化肥的使用量也在逐年增加。然而,有调查表明,仍有相当多的农民朋
为了促进北京市延庆县秋萝卜的合理施肥,提高产量,选择了适宜秋季栽培四季青萝卜,在高、中、低各种肥力水平情况下测土配方施肥。通过试验表明,四季青水果萝卜各种肥力水平配
2013年,于云南省玉溪市设立33.33 hm2有机无机活性肥示范区,与该地按常规处理的非示范区在烟草农艺性状、发病情况2方面进行对比,初步明确其对烟草抗病、增产、保质等方面的
番茄是吉林省长白县蔬菜主栽品种之一,常年栽培,面积较多。近年来,番茄生理性病害的发生呈逐年上升趋势,发生比例(面积)占病害总量的60%以上,给菜农造成了较大损失。由于对生
通过比较试验探究芽后除草油菜施硼及茵核病防治,总结施硼和茵核防治在现蕾期和花期进行油菜施硼及茵核病防治,有效角果多,茵核病发病率低.
A novel intermolecular phosphoryl transfer from O-trimethylsilyl-N-(O, O-diisopropyl) phosphoryl serine trimethylsilyl ester to N, N-bis(trimethylsilyl) histidi
A rapid, simple and accurate method using an immunoaffinity column (IAC) and capillary electrophoresis (CE) for the analysis of the major alkaloids in opium is
Abstract Background Adiponectin, secreted by adipocytes, has been found to be associated with diabetes, obesity and some cardiovascular diseases. Obstructive s
Theimportanceofa pressure flowstudyinthediagnosticwork upof patientssufferingfrombenignprostatichyperplasia (BPH )hasbeenrecognized However,thereisstilluncertai
The density distribution and internal structure of trabecular bone are modulated by local mechanical environment.In this study,an orthotropic adaptation algorit