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Huntington舞蹈病(HD)是一种以慢性进行性舞蹈样运动、精神障碍和痴呆为主要临床特征的神经系统遗传病。多年来,虽然已在病理学和神经化学等方面作了大量工作,但其原发的遗传分子缺陷尚不清楚。新近由于生物物理技术的不断发展,细胞膜理化特性的研究也日趋深入。在对HD患者外周组织细胞如红细胞、淋巴细胞等细胞质膜所进行的研究以后,有人提出
Huntington’s Chorea (HD) is a hereditary genetic disease of the nervous system that is characterized by chronic progressive dance-like movements, mental disorders, and dementia. Over the years, although a great deal of work has been done in the field of pathology and neurochemistry, the defects of the primary genetic molecule are not yet clear. Recently, due to the continuous development of biophysical technology, the research on the physical and chemical properties of cell membranes has also been deepened. After researching the plasma membrane of cells such as erythrocytes and lymphocytes in peripheral blood of HD patients, it was proposed