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目的观察超声引导下肾盂穿刺造瘘治疗梗阻性肾功能不全的临床疗效。方法选择2012年3月至2014年3月收治的88例梗阻性肾功能不全患者。按随机数字表法将患者分为观察组和对照组,各44例。对照组患者给予消石素胶囊、保肾康、潘生丁等药物治疗,观察组患者采用超声引导下肾盂穿刺造瘘治疗。比较两组患者肾功能指标和并发症发生情况。结果对照组患者38例结石排出,梗阻解除,排石成功率为86.36%。观察组44例患者结石梗阻解除,排石成功率为100.00%。治疗1周后,两组患者血清肌酐、尿素氮及尿酸水平均显著下降,差异有统计学意义(P均<0.05),且观察组治疗1周后三项指标均低于对照组(P均<0.05);在治疗4周后,两组患者血清肌酐、尿素氮及尿酸水平均恢复至正常。结论超声引导下肾盂穿刺造瘘治疗梗阻性肾功能不全疗效确切,且安全并发症少。
Objective To observe the clinical effect of ultrasound-guided peritoneal puncture for the treatment of obstructive renal insufficiency. Methods From March 2012 to March 2014, 88 patients with obstructive renal insufficiency were selected. Patients were divided into observation group and control group according to random number table method, 44 cases each. Patients in the control group were treated with oxaliplatin capsules, Baoshenkang, dipyridamole and other drugs. Patients in the observation group were treated with ultrasound-guided peritoneal puncture and fistula. The renal function indexes and complications of the two groups were compared. Results The control group of 38 patients with stone discharge, obstruction removed, the row of stone success rate was 86.36%. Forty-four patients in the observation group were relieved of stone obstruction, and the success rate was 100.00%. After 1 week of treatment, serum creatinine, blood urea nitrogen and uric acid levels decreased significantly in both groups (all P <0.05), and the three indexes in the observation group were lower than those in the control group (P <0.05). After 4 weeks of treatment, serum creatinine, urea nitrogen and uric acid levels returned to normal in both groups. Conclusion Ultrasound guided peritoneal puncture fistula treatment of obstructive renal dysfunction, and less safety complications.