骨肉瘤是恶性骨肿瘤中最常见的一种,好发于四肢长骨的干骺端,肿瘤不易侵犯骺软骨板,并常为骺板所限。骨肉瘤绝大多数都是单发,多源性极为罕见,查国内资料尚未见报道。本院自1965～1973年共收治骨肉瘤患者66例,仅见多源性骨肉瘤1例,特报道如下: 患者李某(住院号108015),女,11岁。主诉:4月前左膝酸痛,行走活动时加重,休息后减轻。11月后于酸痛的膝下方发现一蚕豆大肿块,时隔半月发现腺上方也有一核桃大肿块,2个肿块缓慢地持续增大,酸痛亦随之加剧。近1月 Osteosarcoma is the most common type of malignant bone tumor, occurs in the long bones of the metaphysis, the tumor is not easy to infiltrate the epiphyseal cartilage plate, and is often limited to the epiphyseal plate. The vast majority of osteosarcoma are single, multi-source is extremely rare, check the domestic information has not been reported. The hospital from 1965 to 1973, a total of 66 cases of patients with osteosarcoma, only one case of multi-source osteosarcoma, especially reported as follows: Patient Lee (hospital number 108015), female, 11 years old. Chief Complaint: Left knee pain 4 months ago, aggravating walking activities, relieve after rest. After November, a broad mass of broad bean was found beneath the knee of aching pain. After a half month, a large walnut mass was found above the gland. The two lumps continued to increase slowly and the soreness intensified. Nearly January