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原发性胆汁性肝硬化(Primary Biliary Cirrhosis,PBC)是一种好发于中年女性的肝内小胆管非化脓性炎症,为慢性进行性胆汁淤积性自身免疫性疾病,最终可发展为门脉高压及肝功能衰竭,常伴有其他自身免疫性疾病。PBC发病率约为2～24/10万,国内呈逐年增加趋势。随着临床医生对PBC认识的提高与抗线粒体抗体检测的开展,PBC的确诊病例逐年增多。我们近两年观察到35例,现将其声像图特征总结如下,旨在提高超声医师对该病的超声诊断水平。
Primary Biliary Cirrhosis (PBC) is a non-purulent intrahepatic bile duct inflammation that occurs in middle-aged women. It is a chronic progressive cholestatic autoimmune disease that eventually develops into a door Pulse hypertension and liver failure, often accompanied by other autoimmune diseases. The incidence of PBC is about 2 to 24 per 100 000, the domestic showed an increasing trend year by year. With the improvement of clinicians understanding of PBC and detection of anti-mitochondrial antibodies, the number of confirmed cases of PBC increased year by year. We have observed 35 cases in the recent two years, and now we summarize its sonographic features as follows to improve the sonographer’s level of ultrasound diagnosis of the disease.