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目的探讨循证护理对胃食管反流病患者心理健康和生活质量的影响。方法选择2014年5月~2015年7月50例胃食管反流病患者，采用随机数字表法，将患者随机分为观察组和对照组，每组25例。对照组实施常规护理，观察组采用循证护理，比较两组护理前后心理健康（Zung焦虑自评量表-SAS和抑郁自评量表-SDS）和生活质量（生活质量指数问卷-QL-INDEX）变化。结果护理前，两组SAS、SDS评分比较差异无统计学差异(>0.05)。护理后，观察组SAS、SDS评分明显低于对照组(<0.05)，QL-INDEX中的活动、日常生活、总体精神和总指数评分显著高于对照组(<0.05)。结论循证护理明显改善胃食管反流病患者的心理健康，提高生活质量。“,”Objective To investigate the ef ect of evidence-based nursing on mental health and quality of life in patients with gastroesophageal reflux disease.Methods 50 cases of gastroesophageal reflux disease were randomly divided into the observation group and the control group,25 cases in each group. The control group received routine care, the observation group was given evidence-based nursing. Mental health and quality of life were compared in two goups.Results SAS,SDS scores in the observation group were significantly lower than those in the control group (P<0.05),the scores of activities of daily living,overal mental and overal index in QL-INDEX were significantly higher than those in the control group ( <0.05).Conclusion Evidence-based nursing significantly improved mental health and quality of life in patients with gastroesophageal reflux disease.