利巴韦林系一单磷酸次黄嘌呤核苷脱氢酶强抑制药,广谱抗病毒药,能抑制多种病毒,药物进入被病毒感染的细胞后迅速磷酸化,其磷酸化产物可竞争抑制病毒合成酶,导致细胞内鸟苷三磷酸的减少,阻碍病毒核酸的合成,使病毒的复制和传播受到抑制,产生抗病毒作用。本文探讨利巴韦林肌肉注射治疗儿童手足口病疗效及安全性。1临床资料1.1一般资料2014年4月1日至2015年3月31日,我院 Ribavirin is a strong inhibitor of inosine monophosphate inosine dehydrogenase, a broad-spectrum antiviral agent that inhibits multiple viruses and rapidly phosphorylates drugs into cells infected with the virus, whose phosphorylation products can compete Inhibition of viral synthetase, resulting in the reduction of intracellular guanosine triphosphate, hinder the synthesis of viral nucleic acid, so that the replication and transmission of the virus is inhibited, resulting in antiviral effects. This article explores the efficacy and safety of ribavirin intramuscular injection in children with hand-foot-mouth disease. 1 Clinical data 1.1 General Information April 1, 2014 to March 31, 2015, our hospital