论文部分内容阅读
目的了解江苏省部分地区儿童抗b型流行性感冒(流感)嗜血杆菌荚膜多糖(Hib-PRP)自然抗体水平。方法用酶联免疫吸附试验检测1 429份不同年龄组健康儿童血清的抗Hib多糖抗体。结果抗Hib多糖抗体总阳性率为61.86%,抗体水平随年龄的变化是:新生儿脐带血抗体水平高,1～3月龄下降,4～6月龄降至最低,随后抗体水平随年龄的增长而逐渐增高。结论江苏省部分地区儿童抗Hib多糖抗体水平较高,6月龄抗体水平最低,为Hib疾病的高危人群。
Objective To understand the levels of Hib-PRP natural antibodies against influenza B (influenza) in children in some areas of Jiangsu Province. Methods The serum anti-Hib polysaccharide antibodies of 1 429 healthy children of different ages were detected by enzyme-linked immunosorbent assay (ELISA). Results The positive rate of anti-Hib polysaccharide antibody was 61.86%. The level of antibody with age was high in neonates with umbilical cord blood antibody levels, decreased from 1 to 3 months, and decreased to the lowest from 4 to 6 months. Increase and increase gradually. Conclusion In some areas of Jiangsu Province, children have higher levels of anti-Hib polysaccharide antibodies, with the lowest antibody level at 6 months of age, which is at high risk for Hib disease.