论文部分内容阅读
目的评价福建省医院感染横断面调查结果的趋势变化。方法对2007、2009年两次福建省医院感染横断面调查结果相关指标进行分析。结果 2007年医院感染现患率为3.66%,2009年为3.26%,差异有统计学意义(P<0.01);两次调查中医院感染现患率前5位科室及主要病原菌无明显变化,分别以综合ICU和铜绿假单胞菌最高;手术部位感染现患率由2007年的0.35%下降至2009年的0.25%(P=0.011);其他部位感染现患率则差异无统计学意义;医院感染病原菌以革兰阴性菌为主;抗菌药物使用率由39.22%降至38.28%(P=0.006),其中预防用药比例由41.14%下降至40.79%,治疗用药比例则相应提高,差异有统计学意义(P<0.01),一联用药比例由63.82%提高至67.38%,多联用药有所下降,差异有统计学意义(P<0.01);使用抗菌药物进行治疗前病原学送检率由35.77%提高至42.68%,差异有统计学意义(P<0.01)。结论福建省医院感染控制及抗菌药物管理工作取得了良好的成效。
Objective To evaluate the trend of hospital cross-sectional findings in Fujian Province. Methods The related indexes of two cross-sectional findings of hospital infection in Fujian Province in 2007 and 2009 were analyzed. Results The prevalence rate of nosocomial infection in 2007 was 3.66% and in 2009 was 3.26%, the difference was statistically significant (P <0.01). In the two surveys, there were no significant changes in the top five departments and major pathogens of the prevalence in hospitals, ICU and Pseudomonas aeruginosa; the prevalence of surgical site infections decreased from 0.35% in 2007 to 0.25% in 2009 (P = 0.011); there was no significant difference in prevalence among other sites; (P = 0.006). The proportion of prophylaxis decreased from 41.14% to 40.79%, while the proportion of therapeutic drugs increased correspondingly (P <0.05). The proportion of antimicrobial agents decreased from 39.22% to 38.28% (P = 0.006) 0.01). The proportion of combination therapy increased from 63.82% to 67.38%, while the combination therapy decreased to some extent (P <0.01). The rate of antimicrobial treatment increased from 35.77% to 42.68 %, The difference was statistically significant (P <0.01). Conclusion The hospital infection control and antimicrobial drug management in Fujian Province have achieved good results.