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由于恶性疟原虫对抗疟药产生抗性,使得其感染率在世界范围内持续增加,泰国缅甸边界的恶性疟原虫已发展到对所有曾有效的抗疟药有抗性,这个问题对孕期妇女尤为突出,因为不知道抗疟药对胎儿的具体影响,故对孕妇恶性疟的治疗选择更受限制。本文报道在泰缅边界地区对孕期恶性疟原虫感染用奎宁、甲氟喹和青蒿衍生物(青蒿琥酯和蒿甲醚)进行治疗的研究。
Because Plasmodium falciparum is resistant to antimalarial drugs, making its infection rate increasing worldwide, P. falciparum on the Thai-Burma border has developed resistance to all active antimalarials, a problem that is especially noticeable to pregnant women Prominent, because do not know the specific impact of anti-malarial drugs on the fetus, so the treatment of pregnant women, falciparum malaria choice is more limited. This article reports the use of quinine, mefloquine and derivatives of artemisia (artesunate and artemether) for the treatment of Plasmodium falciparum during pregnancy in the Thai-Myanmar border region.