论文部分内容阅读
目的对80 721例促甲状腺素(TSH)筛查数据进行总结分析,建立一个适合钦州市的TSH切值,以指导后续先天性甲状腺功能减低症(CH)筛查工作。方法以2010版《新生儿疾病筛查技术规范》为操作指南完成筛查工作,使用EXCEL和SPSS 21进行统计学分析。结果综合钦州市气候特点,在CH筛查中的初筛TSH切值在1~3月应采用低温切值8.8μU/ml,在4~12月应采用高温切值7.4μU/ml。在2013-2015年,检测出多个TSH初筛值<10μU/ml的CH患者。结论TSH值的初筛值与该地区温度值密切相关,每个实验室都应该根据实验室所在地的气候条件选择合适的TSH切值。
Objective To summarize the screening data of 80 721 thyrotropin (TSH) screening and establish a TSH value suitable for Qinzhou to guide the follow-up screening of congenital hypothyroidism (CH). Methods Screening was conducted using the 2010 edition of “Neonatal Disease Screening Technical Guidelines” as the operating guide, and statistical analysis was performed using EXCEL and SPSS 21. Results Based on the climatic characteristics of Qinzhou city, the initial screening TSH value in CH screening should be 8.8μU / ml at 1 ~ 3 months and 7.4μU / ml at 4 ~ 12 months. In 2013-2015, multiple CH patients with TSH <10 μU / ml were detected. Conclusion The pre-screening value of TSH value is closely related to the temperature in this area. Each laboratory should choose the appropriate TSH value according to the climatic conditions of the laboratory.