背景 ABO不相容是引起新生儿溶血症的常见原因,其发病率在1/30到1/150之间。除了少数母亲为O型需输血之外,这种溶血几乎不需输血,因为A型和B型的抗-B和抗-A的IgG抗体的反应很弱。尚未见人ABO的IgG抗体序列的报道,部分原因是人IgG混合体难以获得。片段显示技术可能解决这一难题,但它很少用于糖类抗原的研究。研究设计和方法 来自 Background ABO incompatibility is a common cause of neonatal haemolytic disease with an incidence of between 1/30 and 1/150. With the exception of a few mothers with O-type transfusions, this hemolysis requires very little blood transfusions because the responses of type A and type B anti-B and anti-A IgG antibodies are weak. The absence of human ABO IgG antibody sequences has been reported in part because of the difficulty of obtaining human IgG mixtures. Fragment display technology may solve this problem, but it is rarely used for carbohydrate antigen research. Research design and methodology come from