论文部分内容阅读
目的:观察抑肝散治疗儿童注意缺陷多动障碍(ADHD)阴虚阳亢证的临床疗效。方法:将符合本研究纳入和排除标准的94例ADHD患者分为对照组和观察组各47例。两组均采用盐酸哌甲酯片,5 mg/次,2次/d。对照组服用静灵口服液,10 m L/次,2次/d。观察组内服抑肝散,1剂/d。两组疗程均为12周。进行治疗前后斯诺佩评估(SNAP-Ⅳ)量表(父母版),美国康纳(Conner)设计的简易多动症行为评价量表、韦氏智力量表和阴虚阳亢证评分。结果:两组临床疗效经Ridit分析,观察组优于对照组(P<0.05);治疗后观察组SNAP-Ⅳ量表和阴虚阳亢证评分低于对照组(P<0.01);治疗后观察组Conner量表学习、品行、身心障碍、冲动-多动、焦虑及多动指数等因子评分均低于对照组(P<0.01);治疗后观察组韦氏智力量表的言语理解指数(VCI),知觉推理指数(PRI),工作记忆指数(WMI),加工速度指数(PSI),一般能力指数(GAI),认知熟练指数(CPI),总智商(FSIQ)等因子评分均高于对照组(P<0.01)。结论:抑肝散配合盐酸哌甲酯片能降低ADHD儿童阴虚阳亢证,SNAP-Ⅳ评定量表和Conner行为评价量表各因子评分,并能升高韦氏智力量表各因子评分,能改善ADHD的症状,提高患者的智力水平,临床疗效优于静灵口服液。
Objective: To observe the clinical efficacy of Yogan powder in treating children with attention-deficit hyperactivity disorder (ADHD) yin deficiency and hyperactivity syndrome. Methods: Ninety-four patients with ADHD who met the criteria of inclusion and exclusion in this study were divided into two groups: control group and observation group. Both groups were treated with methylphenidate tablets, 5 mg / time, 2 times / d. The control group taking Jingling Oral Liquid, 10 m L / time, 2 times / d. Observation group orally administered liver powder, 1 / d. The two groups were treated for 12 weeks. The SNAP-Ⅳ scale (parent version) before and after treatment, the ADA behavioral assessment scale designed by Conner, the Wechsler Intelligence Scale and the yin deficiency-yang hyperactivity score. Results: The clinical efficacy of the two groups was analyzed by Ridit analysis, the observation group was superior to the control group (P <0.05). After treatment, the score of SNAP-Ⅳ scale and yin deficiency-yang hyperactivity syndrome group was lower than that of the control group (P <0.01) Observer Conner scale learning, behavior, disability, impulsiveness-hyperactivity, anxiety and hyperactivity index and other factors were lower than the control group score (P <0.01); after treatment, weshi scale of intelligence scores of speech comprehension index VCI, PRI, WMI, PSI, GAI, CPI, FSIQ and other factors were all higher than Control group (P <0.01). Conclusion: Yogan powder combined with methylphenidate tablets can reduce Yin deficiency and yin hyperactivity syndrome in children with ADHD, SNAP-Ⅳ rating scale and Conner behavioral rating scale scores of each factor, and can improve the Wechsler Intelligence Scale score of each factor, Can improve the symptoms of ADHD, improve the patient’s intelligence level, clinical efficacy superior to Jingling oral solution.