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目的:探讨呼出气一氧化氮(FeNO)检测在儿童支气管哮喘(AS)诊断中的应用。方法:儿童支气管哮喘患者62例,其中首次诊断支气管哮喘的41例为A组,而规律性应用糖皮质激素达6周以上的支气管哮喘患儿21例为B组,选健康儿童39例为对照组。使用NO测定仪测定FeNO水平,以临床症状和支气管舒张试验为哮喘诊断的金标准。结果:A组为(47.15±31.25)ppb(20.5~69.8p p b);B组为(28.01±17.39) ppb(10.7~38.5p p b);对照组为(12.68±8.80) ppb(6.9~24.2p p b)。F e N O值A组大于B组和对照组(P<0.05)。结论:FeNO对儿童支气管哮喘的诊断和病情评估具有一定的临床应用价值。“,”Objective To study the application of the exhaled nitric oxide (FeNO) detection in diagnosis of bronchial asthma (AS) in children. Methods To select 62 cases of bronchial asthma in children, including 41 cases in diagnosis of bronchial asthma for the first time who are divided into A group , and 21 cases who regularly used the glucocorticoid for 6 weeks or more into B group. At the same time, to select 39 cases of healthy children as the control group. And the FeNO level of these cases was measured by NO measuring instrument, under the gold standard in diagnosis of clinical symptoms and bronchial dilation test.Results The A group was (47.15 ± 31.25) ppb (20.5 ~ 69.8ppb);The B group was (28.01 ± 17.39) ppb (10.7 ~ 38.5ppb);The control group was (12.68 ± 8.80) ppb (6.9 ~ 24.2ppb ). The FeNO value of A group was greater than that in B group and the control group (P<0.05).Conclusion FeNO has a certain clinical value in the diagnosis and assessment of bronchial asthma in children.