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牛红细胞铜锌超氧化物歧化酶经Ｈ＿２Ｏ＿２和抗坏血酸－Ｆｅ￣（３＝）处理后与其相应抗体的反应及与抗狗、抗猪和抗人红细胞铜锌超氧化物歧化酶抗体的交叉反应均显著增强；Ｈ＿２Ｏ＿２－Ｃｕ￣（２＋）和抗坏血酸－Ｆｅ￣（３＋）处理后人血清白蛋白及人ＩｇＧ与其相应抗体的反应也显著增强。结果提示活性氧所致蛋白质抗原与其相应抗体反应的增强可能与某些自身免疫性疾病中抗原抗体复合物的形成有关．
The reaction of bovine erythrocyte copper-zinc superoxide dismutase with its corresponding antibody after H_2O_2 and ascorbate-Fe_ (3 =) treatment and the cross-reaction with anti-dog, anti-pig and anti-human erythrocyte antibody And the response of H 2 O 2-Cu 2+ and ascorbate-Fe 3+ to human serum albumin and human IgG also increased significantly. The results suggest that the increase of reactive oxygen species (ROS) -binding protein antigens to their corresponding antibodies may be related to the formation of antigen-antibody complexes in some autoimmune diseases.