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《神经病学》杂志(Neurology)8月2日发表了一项关于降压药物与阿尔茨海默病(AD)关系的研究,该研究对5种常用降压药物[包括利尿剂、血管紧张素-1受体阻滞剂(ARB)、血管紧张素转换酶抑制剂(ACEI)、钙通道阻滞剂(CCB)和β受体阻滞剂(BB)]与阿尔茨海默病(AD)的发病风险进行了相关性分析,结果表明,在认知正常的受试者中,应用利尿剂、ARB和ACEI均可使AD的发生风险下降,在已经存在轻度认知障碍(MCI)患者中,仅有利尿剂能够使AD的发生风险下降。该研究纳入了2248例患者,所有患者年龄均在75岁
On August 2, Neurology published a study on the relationship between antihypertensive drugs and Alzheimer’s disease (AD), a study of five commonly used antihypertensive drugs [including diuretics, angiotensin (ARB), angiotensin-converting enzyme inhibitors (ACEIs), calcium channel blockers (CCBs) and beta blockers (BBs) and Alzheimer’s disease (AD) The results showed that the use of diuretics, ARB and ACEI could reduce the risk of AD in cognitively normal subjects. In patients with mild cognitive impairment (MCI) , Only diuretics can reduce the risk of developing AD. The study included 2248 patients, all of whom were 75 years of age