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目的 :研究肾宁合剂对IgA肾病临床治疗作用。 方法 :采用随机分组法分别用肾宁合剂及强的松治疗 ,同时观察两组患者 (各 35例 )临床症状、体征、血尿、蛋白尿及免疫球蛋白等指标。结果 :完全缓解率和总有效率治疗组分别为 4 5 7%、97 1% ,对照组分别为 8 6% ,37 1% ,治疗组疗效明显优于对照组(P <0 0 1)。治疗组血尿、蛋白尿改变明显优于对照组 (P <0 0 1和P <0 0 5)。治疗组血清IgA治疗后较治疗前明显降低 (P <0 0 5)。结论 :肾宁合剂对IgA肾病的血尿及蛋白尿有明显治疗作用
Objective: To study the clinical therapeutic effect of Shenning mixture on IgA nephropathy. Methods: Randomized groupings were used respectively with Shenning Mixture and prednisone. At the same time, clinical symptoms, signs, hematuria, proteinuria and immunoglobulin were observed in two groups of patients (35 cases each). Results: The complete remission rate and total effective rate in the treatment group were 45.7% and 97.1%, respectively, and the control group was 86% and 37.1% respectively. The treatment group was significantly better than the control group (P < 0.01). The changes of hematuria and proteinuria in the treatment group were significantly better than those in the control group (P <0 01 and P <0 05). Serum IgA in the treatment group was significantly lower than before treatment (P < 0.05). Conclusion: Shenning Mixture has obvious therapeutic effect on hematuria and proteinuria in IgA nephropathy