因急速时相改变或昼夜交替作业,工人常发生头晕、失眠、食欲不振等不良反应,同时也容易罹患感冒、痢疾、便秘等疾病。作者为了从免疫学角度观察在明晴倒转期间內,作为综合生理机能之一的防御功能所发生的变化,进行了下述实验。实验方法和材料:用4周龄雄性dd系小鼠在溫度25°±1℃,湿度60±5％的明暗交替的人工气候室內,以7时～19时作为亮室,先驯化3周。并将 Due to the rapid change of time or alternating day and night work, workers often have dizziness, insomnia, loss of appetite and other adverse reactions, but also easily suffer from colds, dysentery, constipation and other diseases. In order to observe, from an immunological point of view, the following experiment as a defensive function change which is one of the integrated physiological functions during the inversion of light and light. Experimental Methods and Materials: Male 4-week-old dd mice were acclimatized for 3 weeks in a climate chamber with alternating light and dark at a temperature of 25 ° ± 1 ° C and a humidity of 60 ± 5% with a bright room at 7 o’clock to 19 o’clock. And will