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探讨脑室外引流联合纤溶治疗高血压脑室内出血患者的临床疗效.[方法]回顾性分析本院收治的195例高血压脑室内出血患者的临床资料,根据治疗方式不同将其分为观察组(脑室外引流联合脑室内纤溶治疗,n=98)和对照组(脑室外引流治疗组,n=97).比较两组患者手术情况及两组患者治疗疗效.观察高血压脑室内出血患者术后预后不良发生率.[结果]观察组预后不良发生率低于对照组,差异有统计学意义(χ2=13.387,P<0.001).观察组患者ADL分级Ⅰ~Ⅲ级76例(77.55%)高于对照组的66例(68.04%),差异有统计学意义(χ2=-2.375,P=0.018<0.05).观察组住院时间、脑室外引流拔出时间、术后残余血肿量明显短于对照组,差异有统计学意义(P<0.05).观察组患者术后迟发性脑积水及颅内感染率显著低于对照组,差异无统计学意义(χ2=3.327,P=0.072;χ2=0.423,P=0.515).[结论]脑室外引流联合纤溶治疗高血压脑室内出血患者可改善患者日常生活能力,缩短住院时间,对改善患者预后有重要意义.“,”Toobservetheincidenceofpoorprognosisafterhypertensiveintraventricularhemor-rhage.[Methods]Theclinicaldataof195patientswithhypertensiveintraventricularhemorrhagetreatedinourhos-pitalwereanalyzedretrospectively.Accordingtothedifferenttreatmentmethods,theyweredividedintoobserva-tiongroup (extraventriculardrainagecombinedwithintraventricularfibrinolysis,n=98)andcontrolgroup (ex-traventriculardrainagetreatmentgroup,n=97).Thesurgicalconditionsandthetherapeuticeffectsofthetwo groupswerecompared,andtheincidenceofpoorprognosisinpatientswithhypertensiveintraventricularhemor-rhagewasobserved.[Results]Theincidenceofpoorprognosisintheobservationgroupwaslowerthanthatinthe controlgroup (χ2=13.387,P<0.001).TheADLgradeof76patients (77.55%)intheobservationgroupwas higherthanthatof66patients(68.04%)inthecontrolgroup(χ2=-2.375,P=0.018<0.05).Thehospitaliza-tiontime,theextractiontimeofventriculardrainageandtheamountofresidualhematomaintheobservation groupweresignificantlyshorterthanthoseinthecontrolgroup(P<0.05).Theincidenceofdelayedhydroceph-alusandintracranialinfectionintheobservationgroupwassignificantlylowerthanthatinthecontrolgroup(χ2=3.327,P=0.072;χ2=0.423,P=0.515).[Conclusion]Extraventriculardrainagecombinedwithfibrinolysiscan improvethedailylivingabilityofpatientswithhypertensiveintraventricularhemorrhage,shortenhospitalization time,andimprovetheprognosisofpatientswithimportantsignificance.