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循环肿瘤细胞(circulating tumor cells,CTCs)由原发肿瘤和转移肿瘤灶中的癌细胞播散而来,对CTCs的定量和定性检测可用于肿瘤的早期诊断、转移复发监测、药效分析和生存期预后等方面,在肿瘤预防与治疗中具有重要应用价值。CTCs在肿瘤临床中的应用是当今非常活跃的研究领域,探索新的特异性CTCs分子标志,并研发更加灵敏、高效和特异的CTCs分析新技术,也成为目前研究的热点。本文简要综述了CTCs用于肿瘤防治的研究进展。
Circulating tumor cells (CTCs) are disseminated from cancer cells in primary tumors and metastatic tumorous neoplasms. Quantitative and qualitative detection of CTCs can be used in the early diagnosis of tumors, metastasis recurrence monitoring, drug efficacy analysis and survival Term prognosis, etc., in the prevention and treatment of cancer has an important application value. The application of CTCs in clinical oncology is a very active research field nowadays. Exploring new CTCs molecular markers and developing more sensitive, efficient and specific new technologies for CTCs analysis have also become the hotspot of current research. This article briefly reviewed the research progress of CTCs for cancer prevention and treatment.