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目的:观察奥美拉唑预防脑出血并发应激性溃疡的临床效果。方法:选取收治的脑出血住院患者150例,随机分为治疗组及对照组各75例,两组患者均给予常规治疗。治疗组加用奥美拉唑注射液40 mg静脉推注。结果:治疗1个疗程后治疗组应激性溃疡出血发生率明显低于对照组(P<0.01),死亡病例组间比较,差异有统计学意义(P<0.01)。结论:奥美拉唑可有效预防脑出血并发应激性溃疡出血并降低死亡率,值得临床推广使用。
Objective: To observe the clinical effect of omeprazole in preventing cerebral hemorrhage complicated by stress ulcer. Methods: A total of 150 hospitalized patients with intracerebral hemorrhage were randomly divided into treatment group (75 cases) and control group (75 cases). Both groups were given routine treatment. The treatment group plus omeprazole injection 40 mg intravenous injection. Results: After 1 course of treatment, the incidence of stress ulcer bleeding in the treatment group was significantly lower than that in the control group (P <0.01). There was significant difference between the death groups (P <0.01). Conclusion: Omeprazole can prevent cerebral hemorrhage complicated with bleeding from stress ulcer and reduce mortality, which is worthy of clinical promotion.