Two Novel Sub-skeleton Types of ent-Kauranoids from Isodon gesneroides

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Two novel ent-kauranoids with new sub-skeleton types, gesneroidins G and H were isolated as white powder from the ether extract of the leaves of Isodon gesneroides through normal phase column chromatography. Their structures were elucidated as 3(,6(,7(-triacetoxyl-15-hydroxyl-14-oxo-ent-15,16-seco-kaur-11,17-olide and 1(-hydroxyl-3(,6(,7(,11(-tetraacetoxyl-ent-nor-15,17-kaur-8,16-olide on the basis of the spectral evidences including 1D and 2D NMR spectra.
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