一、概述贲门失弛缓症是一种原发性食管神经肌肉病变所致的食管运动障碍性疾病。以食管体部正常运动消失及吞咽时下食管括约肌(lower esophagealsphincter,LES)松弛不良为特征。本病的发生率约为1/10万,男女发病率相同,成人多见,发生于10～14岁以前的小于5%。本病的发病原因尚 First, an overview Cardiac achalasia is a primary esophageal neuromuscular disease caused by esophageal dyskinesia. It is characterized by loss of normal esophageal motility and poor relaxation of the lower esophageal sphincter (LES) during swallowing. The incidence of the disease is about 1/10 million, the same incidence of men and women, more common in adults, occurred in 10 to 14 years before less than 5%. The incidence of this disease is still