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目的评价标准外伤大骨瓣结合亚低温综合救治重型颅脑损伤的临床效果。方法对急性重型颅脑损伤患者(GCS≤8),治疗组采用外伤性标准大骨瓣结合亚低温冬眠治疗5～7d;对照组仍采用传统的治疗方法。比较两组GCS、GOS、颅内压(ICP)以及并发症。结果治疗组GCS、GOS高于对照组,死亡率、ICP、切口疝、迟发血肿、脑膨出发生率低于对照组。结论标准外伤大骨瓣结合亚低温综合治疗,对降低急性重型颅脑损伤的死亡率、致残率,提高生存质量有重要价值。
Objective To evaluate the clinical effect of standard large trauma combined with mild hypothermia in the treatment of severe craniocerebral injury. Methods Patients with acute severe craniocerebral injury (GCS ≤ 8) were treated with traumatic standard large bone flap combined with mild hypothermia hibernation for 5 to 7 days in the treatment group. The control group was still treated with traditional methods. Two groups of GCS, GOS, intracranial pressure (ICP) and complications were compared. Results The GCS and GOS in the treatment group were higher than those in the control group. The incidence of death, ICP, incisional hernia, delayed hematoma and encephalocele were lower than those in the control group. Conclusions Standard large trauma combined with mild hypothermia can reduce the mortality and morbidity of acute severe craniocerebral injury and improve the quality of life.