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目的 :研究复方栝楼胶囊对兔血清氧化修饰低密度脂蛋白及脂质过氧化的影响。方法 :测定各实验组兔血清中氧化修饰低密度脂蛋白、丙二醛的含量及超氧化物歧化酶的活性。结果 :复方栝楼胶囊组超氧化物歧化酶活性上升 ,丙二醛和氧化修饰低密度脂蛋白含量降低 ,与模型组比较有显著差异。结论 :复方栝楼胶囊能提高机体抗氧化能力 ,减少低密度脂蛋白的氧化修饰 ,抑制脂质过氧化反应。
Objective : To study the effect of compound Genglou capsule on serum oxidized low density lipoprotein and lipid peroxidation in rabbits. Methods: The content of oxidized low-density lipoprotein, malondialdehyde and the activity of superoxide dismutase in serum of rabbits in each experimental group were determined. Results : The activity of superoxide dismutase in compound Xiaolou Capsule group increased, and the content of malondialdehyde and oxidized low density lipoprotein decreased, which was significantly different from the model group. Conclusion : The Compound Genglou Capsule can improve the antioxidant capacity of the body, reduce the oxidation modification of LDL and inhibit the lipid peroxidation.