任何恶性病变事实上都可引起高钙血症,而以乳腺癌、骨髓瘤和肺癌时尤为常见。这些肿瘤一般进展快,经详细的临床检查并配合必要的实验室检查,如骨骼X线摄片、扫描、偶尔进行骨髓穿刺、骨活检等是容易识别的。比较困难的诊断问题是病人罹患“潜伏的肿瘤”,它分泌一种引起高钙血症的物质。这种情况最常见于支气管癌和肾上腺瘤,其他如泌尿生殖道、肝、胰、食道和结肠部位的肿瘤亦须虑 Any malignant disease can in fact cause hypercalcaemia, but especially in breast, myeloma and lung cancers. These tumors generally progress rapidly, after detailed clinical examination and with the necessary laboratory tests, such as bone radiography, scanning, and occasionally bone marrow biopsy, bone biopsy and so is easy to identify. The more difficult diagnostic problem is the patient’s “latent tumor,” which secrete a substance that causes hypercalcaemia. This condition is most common in bronchial and adrenal tumors and in other cancers such as genitourinary tract, liver, pancreas, esophagus and colon