多环芳烃(PAH),尤其是苯骈(a)芘(Bap),对人体是致癌的,根据职业性癌的观察,发现长期接触富有Bap的焦油和沥青的炉顶工人,皮肤癌的发病率比预计高4倍,肺癌高1.5倍。某些PAH,特别是Bap,作用于小鼠、大鼠、田鼠、兔等动物的任何器官和组织、都能引起恶性生长,如皮肤、皮下组织、肺、胃等;各种动物和组织的敏感度不同。小鼠对皮肤癌和肉瘤极敏感,大鼠对皮肤癌的反应较迟钝,大鼠和小鼠胃的腺体部位比覆 Polycyclic aromatic hydrocarbons (PAHs), especially pyrene (BAP), are carcinogenic to the human body. According to the observation of occupational cancer, workers who have been exposed to long-term exposure to Bap-rich tar and bitumen, skin cancer 4 times higher than expected and 1.5 times higher for lung cancer. Some PAH, especially Bap, can cause malignant growth in any organs and tissues of mice, rats, voles, rabbits and other animals, such as the skin, subcutaneous tissues, lungs, stomach and the like; various animal and tissue Different sensitivity. Mice are very sensitive to skin and sarcoma, rats respond more slowly to skin cancer, and the stomach and glands of rats and mice are more affected