肿瘤细胞凋亡过低是肿瘤形成的重要原因之一,诱导肿瘤细胞凋亡也成了目前抗肿瘤治疗的研究方向。用放射性核素标记的annexinV对细胞凋亡后暴露在细胞膜表面的体内PS(膦脂酰丝氨酸)进行体内显像,可检测早期细胞凋亡。这种体内凋亡显像方法可以监测抗肿瘤治疗的疗效、评估患者的预后,甚至可以指导肿瘤治疗方法的选择,提高治疗的质量。 Too low apoptosis of tumor cells is one of the important reasons for tumor formation. Inducing apoptosis of tumor cells has also become the research direction of anti-tumor therapy. In vivo imaging of in vivo PS (phosphatidylserine) exposed to radionuclide-labeled annexin V in apoptotic cells exposed to cell membrane surface can detect early apoptosis. This in vivo apoptosis imaging method can monitor the efficacy of anti-tumor therapy, assess the prognosis of patients, and even guide the selection of tumor treatment methods to improve the quality of treatment.