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目的 研究酸反流量和酸度在反流性食管炎中的作用。方法 对２６ 例对照组及１９例反流性食管炎组进行酸反流量测定，同时进行反流物酸度在Ⅰ级、Ⅱ～Ⅲ级、Ⅳ级反流性食管炎组中的比较。结果 反流性食管炎组与对照组在酸反流量及酸度上有显著性差异 （Ｐ＜ ０．０５）， 反流性食管炎组不同病变严重程度与酸度有相关性 （Ｐ＜ ０．０１）。结论 酸反流量和酸度在反流生食管炎发病机制中占重要地位， 但在病变严重程度上则与酸的浓度密切相关
Objective To study the role of acid reflux and acidity in reflux esophagitis. Methods The acid reflux was measured in 26 cases of control group and 19 cases of reflux esophagitis group. At the same time, the acidity of reflux was compared in grade Ⅰ, Ⅱ ~ Ⅲ, IV grade reflux esophagitis group. Results There was a significant difference in acid reflux and acidity between the reflux esophagitis group and the control group (P <0.05), and the severity of reflux disease was related to the acidity in the reflux esophagitis group (P <0.01) ). Conclusion Acid reflux and acidity play an important role in the pathogenesis of reflux esophagitis but are closely related to the acid concentration in the severity of the disease